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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RUNX3
All Species:
13.03
Human Site:
S338
Identified Species:
26.06
UniProt:
Q13761
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13761
NP_001026850.1
415
44356
S338
H
L
Y
Y
G
T
S
S
G
S
Y
Q
F
S
M
Chimpanzee
Pan troglodytes
XP_001168112
361
38974
G285
L
Y
Y
G
T
S
S
G
S
Y
Q
F
S
M
V
Rhesus Macaque
Macaca mulatta
XP_001113682
501
52667
S424
H
L
Y
Y
G
T
S
S
G
S
Y
Q
F
S
M
Dog
Lupus familis
XP_544492
414
44288
S338
H
L
Y
Y
G
A
S
S
G
S
Y
Q
F
S
M
Cat
Felis silvestris
Mouse
Mus musculus
Q64131
409
43610
G333
A
P
Y
H
L
F
Y
G
A
S
S
G
S
Y
Q
Rat
Rattus norvegicus
Q63046
450
48538
R347
S
A
M
S
S
T
S
R
Y
H
T
Y
L
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001232978
334
36473
L258
T
N
P
S
P
Y
H
L
Y
Y
G
T
S
S
G
Frog
Xenopus laevis
Q6PF39
462
50351
L385
T
S
S
P
S
Y
H
L
Y
Y
G
T
S
A
G
Zebra Danio
Brachydanio rerio
NP_571679
424
45996
S342
H
L
Y
Y
G
T
G
S
G
S
Y
Q
F
S
M
Tiger Blowfish
Takifugu rubipres
NP_001092121
407
44638
G330
S
Y
L
Y
Y
G
T
G
S
G
S
Y
Q
F
S
Fruit Fly
Dros. melanogaster
Q9W349
826
84703
G590
S
V
G
V
G
G
N
G
A
T
M
G
M
G
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q9ATN1
302
31144
V226
G
E
L
A
G
I
A
V
G
A
A
V
T
L
N
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
86.9
63
48.6
N.A.
91.5
59.5
N.A.
N.A.
68.9
56.9
68.1
67.9
23.3
N.A.
N.A.
N.A.
Protein Similarity:
100
86.9
68.2
56.1
N.A.
94.6
70.4
N.A.
N.A.
74.2
69
75.2
77.3
33.1
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
100
93.3
N.A.
13.3
13.3
N.A.
N.A.
6.6
0
93.3
6.6
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
26.6
100
93.3
N.A.
20
13.3
N.A.
N.A.
6.6
6.6
93.3
13.3
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
20
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
30.6
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
9
9
0
17
9
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
9
34
9
0
% F
% Gly:
9
0
9
9
50
17
9
34
42
9
17
17
0
9
17
% G
% His:
34
0
0
9
0
0
17
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
34
17
0
9
0
0
17
0
0
0
0
9
9
0
% L
% Met:
0
0
9
0
0
0
0
0
0
0
9
0
9
9
42
% M
% Asn:
0
9
0
0
0
0
9
0
0
0
0
0
0
0
9
% N
% Pro:
0
9
9
9
9
0
0
0
0
0
0
0
0
9
9
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
34
9
0
9
% Q
% Arg:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% R
% Ser:
25
9
9
17
17
9
42
34
17
42
17
0
34
42
9
% S
% Thr:
17
0
0
0
9
34
9
0
0
9
9
17
9
0
0
% T
% Val:
0
9
0
9
0
0
0
9
0
0
0
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
17
50
42
9
17
9
0
25
25
34
17
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _